The apoptotic cell deaths observed in the adrenal gland of the control group were similar to those observed in the ESWL groups, and apoptosis was occasionally observed around the capsular structure. In the ESWL group, local apoptotic changes were observed in the kidney in the area where the shock wave was focused.
Apoptotic cell deaths in the renal tissue were not observed in the control group under fluorescent microscopy.
Microscopic examination was performed by fluorescent microscopy. Animals were killed at 72 h after the last ESWL, and the tissues were stained with an in situ Cell Death Detection Kit, Fluorescein.
The effect of shock waves on the kidney of male Wistar rats ( n = 12) was investigated in an experimental setting using a special ESWL device. This study was designed to investigate whether exposure to short-term extracorporeal shock wave lithotripsy (ESWL) produces histologic changes or induces apoptosis in the kidney, adrenal glands or diaphragm muscle in rats.
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